Australia require after diminishing England in tea on day five of the first Test at Old Trafford to 166-6 four wickets in the final session to retain the Ashes.
England, who had resumed on 18-2, lost Jason Roy (31) and Ben Stokes (1) at the morning and also Joe Denly (53) and Jonny Bairstow (25) from the afternoon.
Pat Cummins believed he had completed a five-for if he had Craig Overton (12no) given out lbw, just for the choice to be clubbed with the ball hitting the England man beyond the line.
The hosts are planning to bat out the last day of a Test to earn a draw for the first time since doing so in New Zealand at 2013 and, with Jos Buttler (30no) at the crease, still have hope.
If Australia win, then they can proceed 2-1 up in the series with one match to play and turn into the flying side to depart England as Ashes holders as the Steve team of 2001.
Cummins struck twice having Stokes while Nathan Lyon had pouched at short leg at second caught behind before Mitchell Starc trapped Bairstow lbw and bowling Roy.
Cummins had begun the victory push Saturday evening, if he dislodged Joe Root and Rory Burns for ducks from deliveries, decreasing England to 0-2 four chunks in their innings.
Watch lasted coverage on Sky Sports The Ashes along with Sky Sports Main Event from day five of the fourth Ashes Test.